➤ Reproducibility: It must be possible to multiply the stem cells in sufficient quantities in culture.
➤ Differentiability: It must be possible to stimulate them to differentiate into the required cell type in great numbers.
➤ Purity: It must be possible to obtain differentiated cells of a single cell type, not cell mixtures.
➤ Precise integration: It must be possible to transplant the cell or tissue replacement to the correct site in the body.
➤ Safety against tumor formation: It must be ensured that the transplants do not continue to grow uncontrolled or form tumors.
➤ Long-term therapeutic effectiveness: The transplants must prove their functionality in the organism and have a therapeutic effect over a longer period of time.
➤ Immunocompatibility: Cell transplants should not be rejected by the immune system of the recipient organism.